The Toxico Spider can attack normally, add 2% to his attack, or attack everybody--with moderate to high damage.
A high damage dealer and a healer is advised. However, if you can kill it fast enough, a healer isn't really needed.
|Fury Sabre||Teacher Necklace||Giant Spider Leg|
|Iron Fist||Winged Rapier||Toxic Hat Badge|
|Maltrecho Book||Closed Conquistador Helmet||Beast Gem|
|Cloud Walker||Army Bow||Greater Luck Gem|
|Red Dragon Sword|
Toxico Spider is of a Beast element, and is therefore weak against Fire, Light, and Earth, and strong against Plant and Mechanic.